Biohaskell

bioinformatics and haskell

454 sequencing and parsing the SFF binary format

Roche’s 454 sequencing technology can produce biological sequence data on a scale that exceeds traditional Sanger sequencing by orders of magnitude.   Due to the fundamentally different method used to generate the sequences, we would like to investigate the raw data and see if we can quantify — and maybe also reduce the number or severity [...]